Translational repression: Not just a Puf of smoke
نویسنده
چکیده
Proteins containing Puf domains interact with cofactors to form complexes that bind RNAs and control diverse developmental events. Recent studies have shed light on how the Puf family of proteins regulates mRNA activity.
منابع مشابه
A role for the poly(A)-binding protein Pab1p in PUF protein-mediated repression.
PUF proteins regulate translation and mRNA stability throughout eukaryotes. Using a cell-free translation assay, we examined the mechanisms of translational repression of PUF proteins in the budding yeast Saccharomyces cerevisiae. We demonstrate that the poly(A)-binding protein Pab1p is required for PUF-mediated translational repression for two distantly related PUF proteins: S. cerevisiae Puf5...
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عنوان ژورنال:
- Current Biology
دوره 11 شماره
صفحات -
تاریخ انتشار 2001